(2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid
cis-4-hydroxy-L-proline
CAS: 618-27-9
Molecular Formula: C5H9NO3
(2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid - Names and Identifiers
| Name | cis-4-hydroxy-L-proline |
| Synonyms | CHP CHYP CIS-HYP-OH CIS-HYDROXYPROLINE L-ALLO-HYDROXYPROLINE CIS-L-4-HYDROXYPROLINE CIS-4-HYDROXY-L-PROLINE cis-4-hydroxy-L-proline L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLIC ACID L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLLIC ACID (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid (2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid |
| CAS | 618-27-9 |
| EINECS | 210-542-1 |
| InChI | InChI=1/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3?,4-/m0/s1 |
| InChIKey | PMMYEEVYMWASQN-IMJSIDKUSA-N |
(2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid - Physico-chemical Properties
| Molecular Formula | C5H9NO3 |
| Molar Mass | 131.13 |
| Density | 1.3121 (rough estimate) |
| Melting Point | 257 °C (dec.) (lit.) |
| Boling Point | 242.42°C (rough estimate) |
| Specific Rotation(α) | -59 º (c=2, H2O) |
| Water Solubility | soluble |
| Solubility | soluble |
| Appearance | Powder |
| Color | White to beige |
| Merck | 14,4840 |
| BRN | 81440 |
| pKa | 2.14±0.40(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | -59 ° (C=2, H2O) |
| MDL | MFCD00064319 |
| Use | Amanita is a component of sp. polypeptide toxin, but unlike collagen, it is not an animal protein. |
(2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| TSCA | Yes |
| HS Code | 29339900 |
(2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid - Reference
| Reference Show more | 1. [IF=2.193] Yang Yang et al."Simultaneous Determination of 34 Amino Acids in Tumor Tissues from Colorectal Cancer Patients Based on the Targeted UHPLC-MS/MS Method."J Anal Methods Chem. 2020;2020:4641709 |
(2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid - Introduction
Soluble in water, slightly soluble in alcohol, insoluble in ether.
Last Update：2022-10-16 17:27:12
(2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | cis-4-Hydroxy-L-proline, a proline analog that is an inhibitor of collagen production. cis-4-Hydroxy-L-proline can inhibit the growth of fibroblasts by preventing the deposition of the three layers of spiral collagen on the cell layer. cis-4-Hydroxy-L-proline also inhibited the growth of primary N-nitrosomethylurea-induced breast tumors in rats. |
| purpose | Amanita sp. A component of a polypeptide toxin, but unlike collagen, it is not an animal protein |
Last Update：2024-04-10 22:30:50
Supplier List
Spot supply
Product Name: Proline Impurity 16 Visit Supplier Webpage Request for quotationCAS: 618-27-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Cis-4-Hydroxy-L-proline Visit Supplier Webpage Request for quotationCAS: 618-27-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Proline Impurity 16 Visit Supplier Webpage Request for quotationCAS: 618-27-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Cis-4-Hydroxy-L-proline Visit Supplier Webpage Request for quotationCAS: 618-27-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History